PIN108 Sustained Virological Response as Patient-Relevant Endpoint in Hepatitis C?
نویسندگان
چکیده
منابع مشابه
Hepatitis C reinfection after sustained virological response.
BACKGROUND & AIMS On-going risk behaviour can lead to hepatitis C virus (HCV) reinfection following successful treatment. We aimed to assess the incidence of persistent HCV reinfection in a population of people who inject drugs (PWID) who had achieved sustained virological response (SVR) seven years earlier. METHODS In 2004-2006 we conducted a multicentre treatment trial comprising HCV genoty...
متن کاملHepatocellular Carcinoma in a Non-cirrhotic Patient with Sustained Virological Response after Hepatitis C Treatment
Chronic infection by hepatitis C virus (HCV) is one of the main risk factors for the development of liver cirrhosis and hepatocellular carcinoma. However, the emergence of hepatocellular carcinoma (HCC) in non-cirrhotic HCV patients, especially after sustained virological response (SVR) is an unusual event. Recently, it has been suggested that HCV genotype 3 may have a particular oncogenic mech...
متن کاملHepatitis C virus reinfection among prisoners with sustained virological response after treatment for chronic hepatitis C.
BACKGROUND & AIMS We estimated HCV reinfection rate and its associated risk factors in inmates with chronic hepatitis C who had achieved sustained virological response (SVR) after completing combination therapy while in prison. METHODS Individuals who had achieved an SVR after treatment provided from January 2003 to December 2009 at four prisons in Catalonia, had been tested annually for HCV ...
متن کاملSustained and rapid virological responses in hepatitis C clinical trials
Direct-acting antivirals (DAAs) in combination with pegylated IFN-a and ribavirin drastically improve the rates of rapid virological response (RVR) and sustained virological response (SVR) in the treatment of chronic hepatitis C virus infection, specifically in difficult-to-cure hepatitis C virus genotype 1. At present, RVR is an important milestone highly predictive of SVR. Response-guided the...
متن کاملSustained virological response is associated with clearance of hepatitis C virus RNA and a decrease in hepatitis C virus antibody
BACKGROUND/AIM Viral eradication in chronic hepatitis C patients with sustained virological response (SVR) after interferon (IFN) therapy remains controversial. METHODS During a long-term follow-up study, 157 patients with SVR to IFN-alpha-2b-based therapy were investigated with a transcription-mediated amplification (TMA) assay in serum. The hepatitis C virus (HCV) antibody was assessed by m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Value in Health
سال: 2011
ISSN: 1098-3015
DOI: 10.1016/j.jval.2011.08.294